Programme

Mon 26 April 2010
08:00 20:00		Registration

08:45 10:15		Symposium 10: Novel aspects in the treatment of bone disease Room: Main Auditorium Chairs: D. Bassett (UK) & L. Hofbauer (Germany)
08:45	S10.1	Principles of bone biology (the major pathways, RANKL, SOST, Wnt etc) G. Russell (UK)
09:15	S10.2	Preclinical and clinical effects of RANK ligand inhibition S. Ferarri (Switzerland)
09:45	S10.3	Teriparatide and parathyroid hormone in the treatment of ostoporosis M. Kraenzlin (Switzerland)

08:45 10:15		Symposium 11: Premature Ovarian Failure (POF) Room: Forum Hall Chairs: C. Andersen (Denmark) & J. Young (France)
08:45	S11.1	A pivotal role for NR5A1 in human reproductive processes A. Bashamboo (France)
09:05	S11.2	Premature ovarian failure due to overactivation of primordial follicles in mice K. Liu (Sweden)
09:25	S11.3	Ovarian AMH - Implications for the diagnosis of premature ovarian failure A. Themmen (The Netherlands)
09:45	S11.4	Genetic defects in ovarian growth/differentiation factors L. Persani (Italy)

08:45 10:15		Symposium 12: Thyroid hormone metabolism and action: new developments Room: Meeting Hall I Chairs: J. Koehrle (Germany) & A. Aranda (Spain)
08:45	S12.1	Thyroid hormone transporters E. Friesema (The Netherlands)
09:05	S12.2	Life without T4 to T3 conversion V. Galton (USA)
09:25	S12.3	Thyroid hormone signalling in the heart W. Simonides (The Netherlands)
09:45	S12.4	Significance of thyroid receptor alpha in metabolism J. Mittag (Sweden)

08:45 10:15		Oral Communications 3: Pituitary Room: Panorama Hall Chairs: P. Vlcek (Czech Republic) & F. Kelestimur (Turkey)
08:45	OC3.1	Sgk1 effects on POMC transcription and ACTH release are opposite to those of glucocorticoids Presenter: Marie Helene Reiter M Reiter; G Vila; S Baumgartner-Parzer; E Knosp; L Wagner; G Stalla; A Luger;
09:00	OC3.2	Copeptin, an arginine vasopressin (AVP) marker, as a diagnostic aid in SIADH of cancer Presenter: Kashinath Dixit K Dixit; N Morgenthaler; G Brabant;
09:15	OC3.3	Trauma severity, but not hypopituitarism, affects cognitive function after traumatic brain injury: a multi-center study in the Netherlands. Presenter: Nieke Kokshoorn N Kokshoorn; J Smit; W Nieuwlaat; N Biermasz; P Bisschop; R Veldman; F Roelfsema; A Franken; M Wassenaar; J Tiemensma; J Romijn; A Pereira;
09:30	OC3.4	Influence of the d3-GH receptor polymorphism on the metabolic and biochemical phenotype of GH deficient adults at baseline and during short- and long-term rhGH replacement therapy. Presenter: Claudia Giavoli C Giavoli; E Ferrante; E Profka; L Olgiati; S Bergamaschi; C Ronchi; E Verrua; M Filopanti; E Passeri; L Montefusco; A Lania; S Corbetta; M Arosio; B Ambrosi; A Spada; P Beck-Peccoz;
09:45	OC3.5	Cortisol, but not ACTH/CRH, increases circulating ghrelin in man Presenter: Ibrahim Azzam I Azzam; R Limor; N Stern; Y Greenman;
10:00	OC3.6	Young Patients with Sporadic Macroadenomas as target population for AIP mutations screening Presenter: Maria Tichomirowa M Tichomirowa; A Barlier; A Daly; M Jaffrain-Rea; R Cozzi; M Yaneva; L Naves; C Ronchi; C Sievers; D Maiter; C Montañana; S Zacharieva; A Beckers;

10:15 11:00		Plenary Lecture 3 Room: Main Auditorium Chairs: I. Huhtaniemi (UK) & M. Tena-Sempere (Spain)
10:15	PL3	Novel regulator of Gonadotropin R. Millar (UK)

11:00 11:15		Coffee Break and Exhibition Room: Exhibition Hall

11:15 12:45		Symposium 13: The TSH Reference Range Room: Main Auditorium Chairs: P. Laurberg (Denmark) & I. Zosin (Romania)
11:15	S13.1	Determinants of the TSH reference range H. Voelzke (Germany)
11:35	S13.2	Health outcomes related to TSH values within the reference range B. Asvold (Norway)
11:55	S13.3	A critical synopsis of current meta-analyses in the field of subclinical thyroid disease B. Velkeniers (Belgium)
12:15	S13.4	Solving the dilemma: what to do as a simple clinician S. Mariotti (Italy)

11:15 12:45		Symposium 14: Novel actions of vitamin D Room: Forum Hall Chairs: M. Pfeifer (Slovenia) & M. Kraenzlin (Switzerland)
11:15	S14.1	Vitamin D and Diabetes C. Mattieu (Belgium)
11:35	S14.2	Vitamin D and wnt signalling in colon cancer A. Munoz (Spain)
11:55	S14.3	Vitamin D dependent anti-microbio pathways M. Hewison (USA)
12:15	S14.4	Vitamin D and differentiation of mesenchymal stem cells and osteoblasts H. van Leeuwen (The Netherlands)

11:15 12:45		Symposium 15: Wnt Signalling Room: Meeting Hall I Chairs: M. Tena-Sempere (Spain) & C. Stratakis (USA)
11:15	S15.1	Wnt/Beta-Catenin Controls Stem Cells in Regeneration and Tumor Formation W. Birchmeier (Germany)
11:45	S15.2	Wnt signaling and the metabolic syndrome S. Schinner (Germany)
12:15	S15.3	Adipogenesis, diabetes and wnt signaling J. Sethi (UK)

11:15 12:45		Oral Communications: Highlights 1 Room: Panorama Hall Chairs: W. Arlt (UK) & A. Tsatsoulis (Greece)
11:15	H1.1	PEX11beta deficiency impaired ossification by indirectly activating PPARgamma expression and diminishing Runx2 activity Presenter: Guofeng Qian
11:30	H1.2	Novel pathogenetic pathways of adrenocortical tumors revealed by meta-analysis of genomics data Presenter: Peter Igaz
11:45	H1.3	Frequent phosphodiesterase 11a (pde11a4) gene mutations in patients with carney complex (cnc) due to prkar1a mutations and adrenal (ppnad) and sertoli cell tumors (lccsct): a digenic disorder? Presenter: Rossella Libe
12:00	H1.4	Physiological rescue by functional complementation of mutated luteinising hormone receptors in transgenic mice Presenter: Adolfo Rivero-Müller
12:15	H1.5	Different genes are involved in Pendred’s Syndrome and in Enlarged Vestibular Aqueduct Syndrome Presenter: Valentina Cirello

13:00 14:30		Lunch & Exhibition ESE President Meets New Members of the ESE (Invitation Only) Room: Exhibition Hall

13:00 15:30		Poster session: Talk to me!

13:00 14:30		Debate 2: This house believes that it is important to investigate patients with suspected primary hyperaldosteronism Room: Main Auditorium Chairs: M. Reincke (Germany) & J. Widimsky (Czech Republic) For: G. Rossi (Italy) & Against: K. Cruikshank (UK)

13:00 14:00		Meet the Expert 9: Primary hyperparathyroidism: when to intervene? Room: Forum Hall C. Marcocci (Italy)

13:00 14:00		Meet the Expert 10: High throughput mouse phenotyping with metabolomics Room: Meeting Hall I J. Adamski (Germany)

13:00 14:00		Meet the Expert 11: Clinical approach to male infertility Room: Panorama Hall C. Krausz (Italy)

13:00 14:00		Meet the Expert 12: The Zebrafish model Room: Meeting Hall IV V. Laudet (France)

14:30 15:30		Meet the Expert 13: Subclinical Hypothyroidism: to treat or not to treat Room: Forum Hall V. Fadeyev (Russia)

14:30 15:30		Meet the Expert 14: Practical management of Diabetes Room: Meeting Hall I J. Vassallo (Malta)

14:30 15:30		Meet the Expert 15: Genetic and Genomic Studies in Endocrinology Room: Meeting Hall IV A. Uitterlinden (The Netherlands)

14:30 15:30		Meet the Expert 16: Secondary Osteoporosis Room: Meeting Hall IV J. Stepan (Czech Republic)

15:30 17:00		Symposium 16: Hot Topics in Pituitary Disease Room: Main Auditorium Chairs: C. Strasburger (Germany) & G. Lombardi (Italy)
15:30	S16.1	Pros and Cons of large scale screening of Cushing's syndrome A. Tabarin (France)
16:00	S16.2	The safety of dopamine agonists - Clinical perspective A. Pereira (The Netherlands)
16:30	S16.3	Problems with GH and IGF-1 assays: progress? M. Bidlingmaier (Germany)

15:30 17:00		Symposium 17: Genetic basis of infertility: Clinical studies and animal models Room: Forum Hall Chairs: P. Bouchard (France) & K. Liu (Sweden)
15:30	S17.1	Genetically modified mouse models for the analysis of reproductive disorders W. Colledge (UK)
16:00	S17.2	Neurokinin B signalling in human puberty A.K. Topaloglu (Turkey)
16:30	S17.3	Genetics of Kallmann syndrome C. Dode (France)

15:30 17:00		Oral Communications 4: Adrenals Room: Meeting Hall I Chairs: S. Tsagarakis (Greece) & E. Husebye (Norway)
15:30	OC4.1	Subtype differentiation in primary hyperaldosteronism – evaluation of alternative algorithms avoiding a controversial gold standard Presenter: Katharina Lang K Lang; S Hahner; O Vonend; L Rump; M Quninkler; S Diederich; K Maier; F Beuschlein; M Bidlingmaier; S Endres; C Engelke; R Kickuth; M Fassnacht; M Reincke; B Allolio;
15:45	OC4.2	A mouse model with hyperaldosteronism carrying an ENU induced mutation on chromosome 9 Presenter: Ariadni Spyroglou A Spyroglou; S Wagner; M Bidlingmaier; T Bozoglu; B Rathkolb; A Schrewe; M Angelis; F Beuschlein;
16:00	OC4.3	Novel mutations in the glucocorticoid receptor gene : from familial bilateral adrenal hyperplasia to glucocorticoid receptor haploinsufficiency Presenter: Jacques Young J Young; S Trabado; J Bouligand; L Amazit; S Viengchareun; A Guichon-Mantel; B Delemer; M Lombes;
16:15	OC4.4	Combined anticortisolic therapy by metyrapone, ketoconazole and mitotane: an alternative to adrenalectomy in severe Cushing’s syndrome Presenter: Peter Kamenicky P Kamenicky; C Droumaguet; E Baudin; S Salenave; S Trabado; L Cazabat; P Chanson; J Young;
16:30	OC4.5	Effects of mitotane on testicular adrenal rest tumors size, sperm count and adrenal steroidogenesis in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency Presenter: Anne Bachelot A Bachelot; S Salenave; R Renard; L Rocher; J Dulon; C Coussieu; S Brailly-Tabard; Y Morel; P Touraine; J Young;
16:45	OC4.6	Serum Cortisol Predicts Increased Cardiovascular Mortality in Patients with Acute Coronary Syndrome Presenter: Andreas Tomaschitz A Tomaschitz; S Pilz; E Ritz; T Grammer; C Drechsler; B Boehm; W Maerz;

15:30 17:00		Oral Communication Highlights 2 Room: Panorama Hall Chairs: P. Beck-Peccoz (Italy) & P. Igaz (Hungary)
15:30	H2.1	The endocannabinoid action in the regulation of energy balance is mainly due to the CB1 receptor in the forebrain neurons Presenter: Carmelo Quarta
15:45	H2.2	Human recombinant GH replacement therapy in children with pseudohypoparathyroidism type Ia and GH deficiency: first study on the effect on growth Presenter: Giovanna Mantovani
16:00	H2.3	Subtle cognitive impairments in patients with long-term cure of Cushing’s disease Presenter: Jitske Tiemensma
16:15	H2.4	TAC3 and TACR3 “Knockouts” Cause Hypothalamic Congenital Hypogonadotropic Hypogonadism in Humans Presenter: Jacques Young
16:30	H2.5	Effects of leptin administration on starvation-induced alterations in hepatic thyroid hormone metabolism in mice. Presenter: Anita Boelen

17:00 17:15		Coffee Break and Exhibition Room: Exhibition Hall

17:15 18:00		Plenary Lecture 4 Room: Main Auditorium Chairs: W. Wiersinga (The Netherlands) & TBC
17:15	PL4	Thyronamines: Beyond T4 and T3 T. Scanlon (USA)

18:15 19:45		Satellite Symposium: Understanding and management of primary hyperparathyroidism: anything new? Sponsored by Amgen Room: Panorama Hall Chair: John Bilezikian (USA)
18:15		Welcome from the chair John Bilezikian (USA)
18:20		PHPT: prevalence and clinical presentation today Jens Bollerslev (Norway)
18:50		Non-traditional features of modern PHPT John Bilezikian (USA)
19:20		Management of PHPT: What matters most? Claudio Marcocci (Italy)
19:45		Close of meeting

18:15 19:45		Satellite Symposium: Hypontraemia: is treatment necessary? An interactive forum. Sponsored by Otsuka Room: Meeting Hall I Chair: Paolo Beck-Peccoz
18:15		Welcome and introduction Paolo Beck-Peccoz
18:20		Mild and moderate hyponatraemia - is treatment necessary? Chris Thompson
18:45		New approaches to the diagnosis of hyponatraemia Bruno Allolio
19:05		Considering new treatments in the management of hyponatraemia: Case study highlights Joseph Verbalis
19:35		Questions and answers

18:15 19:45		Satellite Symposium: Clinical insights on pituitary tumours Sponsored by Novartis Room: Forum Hall Chair: Michael Sheppard (UK)
18:15		A review of current practice and outcomes from patients with pituitary tumors Michael Sheppard (UK)
18:45		Achieving optimal outcomes for the patient with Acromegaly Anna Maria Colao (Italy)
19:15		Strategies for improving outcomes for the patient with Cushings disease Richard Feelders (The Netherlands)

20:30		ECE 2010 Informal Social Evening